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鄂式破碎机nckx

颚式破碎机百度百科

Jaw Crusher 别名鄂破、老虎口性能最常用的矿石破碎机优点效率高分类单摆颚式、复摆颚式目录 1 发展概况 2 简介 3 分类单摆颚式原理复摆颚式原理 4 优点 5 操作步骤 6 颚式破碎机百度百科Jaw Crusher 别名鄂破、老虎口性能最常用的矿石破碎机优点效率高分类单摆颚式、复摆颚式目录 1 发展概况 2 简介 3 分类单摆颚式原理复摆颚式原理 4 优点 5 操作步骤 6

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实验室鄂式破碎机-南昌科鑫制样设备有限公司

南昌科鑫制样设备有限公司专业供应销售实验室鄂式破碎机系列产品，公司具有良好的市场信誉，专业的销售和技术服务团队,凭着经营实验室鄂式破碎机系列多年实验室鄂式破碎机-南昌科鑫制样设备有限公司南昌科鑫制样设备有限公司专业供应销售实验室鄂式破碎机系列产品，公司具有良好的市场信誉，专业的销售和技术服务团队,凭着经营实验室鄂式破碎机系列多年

鄂式破碎机设备_百度百科

鄂式破碎机工作方式为曲动挤压型，其工作原理是：电动机驱动皮带和皮带轮，通过偏心轴使动颚上下运动，当动颚上升时肘板与动颚间夹角变大，从而推动动颚板向固定颚板接鄂式破碎机设备_百度百科鄂式破碎机工作方式为曲动挤压型，其工作原理是：电动机驱动皮带和皮带轮，通过偏心轴使动颚上下运动，当动颚上升时肘板与动颚间夹角变大，从而推动动颚板向固定颚板接

鄂式破碎机适用范围与用途简介

鄂式碎石机用途和使用范围：. 1、该系列鄂式破碎机主要用于化工、水泥、冶金、矿山、建筑、耐火材料及陶瓷等工业部门作中碎和细碎各种中硬矿石和岩石用。. 2、该系列颚式鄂式破碎机适用范围与用途简介鄂式碎石机用途和使用范围：. 1、该系列鄂式破碎机主要用于化工、水泥、冶金、矿山、建筑、耐火材料及陶瓷等工业部门作中碎和细碎各种中硬矿石和岩石用。. 2、该系列颚式

鄂式破碎机 NCKX-5-443-矿山破碎设备网

鄂式破碎机/高效鄂式破碎机/粗碎鄂式破碎机/pex鄂式破碎机详细介绍：鄂式破碎机/高效鄂式破碎机/粗碎鄂式破碎机/pex鄂式鄂式破碎机 NCKX-5-443-矿山破碎设备网鄂式破碎机/高效鄂式破碎机/粗碎鄂式破碎机/pex鄂式破碎机详细介绍：鄂式破碎机/高效鄂式破碎机/粗碎鄂式破碎机/pex鄂式

细胞分裂素氧化酶脱氢酶的生理生化和分子特性

植物生理学通讯第44卷第4 期，2008年8 月 797 细胞分裂素氧化酶/ 脱氢酶的生理生化和分子特性张芬, 郭得平*, 林明丽, 闫淼淼浙江大学农业与生物技术学院园艺系, 杭州310029 细胞分裂素氧化酶脱氢酶的生理生化和分子特性植物生理学通讯第44卷第4 期，2008年8 月 797 细胞分裂素氧化酶/ 脱氢酶的生理生化和分子特性张芬, 郭得平*, 林明丽, 闫淼淼浙江大学农业与生物技术学院园艺系, 杭州310029

The Na+/Ca2+, K+ exchanger 2 modulates mammalian

The dominant view has been that the cone-specific isoform of the Na + /Ca 2+, K + exchanger, NCKX2, is responsible for removing Ca 2+ from their outer segments. However, indirect evaluation of The Na+/Ca2+, K+ exchanger 2 modulates mammalian The dominant view has been that the cone-specific isoform of the Na + /Ca 2+, K + exchanger, NCKX2, is responsible for removing Ca 2+ from their outer segments. However, indirect evaluation of

Potassium-dependent sodium-calcium exchanger (NCKX) isoforms

K +-dependent Na + /Ca 2+-exchangers (NCKX) are a relatively recently described five-member gene family of transporters which play a quantitatively significant role in neuronal Ca 2+ transport. In this review we highlight the important individual contributions these transporters make to cellular Ca 2+ homeostasis and neuronal function. Notably, different Potassium-dependent sodium-calcium exchanger (NCKX) isoforms K +-dependent Na + /Ca 2+-exchangers (NCKX) are a relatively recently described five-member gene family of transporters which play a quantitatively significant role in neuronal Ca 2+ transport. In this review we highlight the important individual contributions these transporters make to cellular Ca 2+ homeostasis and neuronal function. Notably, different

The Na+/Ca2+ exchanger NCKX4 governs termination and

Here the authors identify NCKX4, a potassium-dependent Na+/Ca2+ exchanger as being necessary for rapid response termination and proper adaptation of vertebrate olfactory sensory neurons. They also The Na+/Ca2+ exchanger NCKX4 governs termination and Here the authors identify NCKX4, a potassium-dependent Na+/Ca2+ exchanger as being necessary for rapid response termination and proper adaptation of vertebrate olfactory sensory neurons. They also

Searching for a Role of NCX/NCKX Exchangers in Neurodegeneration

Because NCKX reversal inhibitors are not yet available, the precise role of NCKX proteins in ischemic death of CA1 neurons remains to be established . The involvement of NCX exchangers in brain pathologies has been related to at least three main conditions including cerebral hypoxia–anoxia episodes, nerve injury, and Searching for a Role of NCX/NCKX Exchangers in NeurodegenerationBecause NCKX reversal inhibitors are not yet available, the precise role of NCKX proteins in ischemic death of CA1 neurons remains to be established . The involvement of NCX exchangers in brain pathologies has been related to at least three main conditions including cerebral hypoxia–anoxia episodes, nerve injury, and

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone

Here, we show that the Na + /Ca 2+, K + exchanger NCKX4 is expressed in zebrafish, mouse, and primate cones. Functional analysis of NCKX4-deficient mouse cones revealed that this exchanger is essential for the wide operating range and high temporal resolution of cone-mediated vision. We show that NCKX4 shapes the cone The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient coneHere, we show that the Na + /Ca 2+, K + exchanger NCKX4 is expressed in zebrafish, mouse, and primate cones. Functional analysis of NCKX4-deficient mouse cones revealed that this exchanger is essential for the wide operating range and high temporal resolution of cone-mediated vision. We show that NCKX4 shapes the cone

IJMS Free Full-Text Structure-Based Function and Regulation

The NCKX proteins mediate the K +-dependent Na + /Ca 2+ exchange by transporting 1Ca 2+ + 1K + in exchange for 4Na + ions [45,46,47]. The differences in ion selectivity and the ion-exchange stoichiometry between the NCXs (3Na + :1Ca 2+ ) and NCKXs (4Na + :1Ca 2+ ,1K + ) are quite amazing since ten (out of twelve) ion IJMS Free Full-Text Structure-Based Function and RegulationThe NCKX proteins mediate the K +-dependent Na + /Ca 2+ exchange by transporting 1Ca 2+ + 1K + in exchange for 4Na + ions [45,46,47]. The differences in ion selectivity and the ion-exchange stoichiometry between the NCXs (3Na + :1Ca 2+ ) and NCKXs (4Na + :1Ca 2+ ,1K + ) are quite amazing since ten (out of twelve) ion

Calmodulin binds and modulates K+-dependent Na+/Ca2

The family of K +-dependent Na + /Ca 2+-exchangers, NCKX, are important mediators of cellular Ca 2+ efflux, particularly in neurons associated with sensory transduction. The NCKX family comprises five proteins, NCKX1-5, each being the product of a different SLC24 gene. NCKX4 (SLC24A4) has been found to have a critical role in termination and Calmodulin binds and modulates K+-dependent Na+/Ca2The family of K +-dependent Na + /Ca 2+-exchangers, NCKX, are important mediators of cellular Ca 2+ efflux, particularly in neurons associated with sensory transduction. The NCKX family comprises five proteins, NCKX1-5, each being the product of a different SLC24 gene. NCKX4 (SLC24A4) has been found to have a critical role in termination and

Potassium-dependent sodium/calcium exchanger 3 (Nckx3 PubMed

Both Nckx3 +/-and Nckx-/-mice also exhibited deficits in sociability and social novelty preference. Furthermore, Nckx-/-mice displayed increased depression-related behavior. However, there was no significant change in cognition function detected in Nckx-/-mice. This study demonstrates that NCKX3 is involved in behavior and neuronal function. Potassium-dependent sodium/calcium exchanger 3 (Nckx3 PubMedBoth Nckx3 +/-and Nckx-/-mice also exhibited deficits in sociability and social novelty preference. Furthermore, Nckx-/-mice displayed increased depression-related behavior. However, there was no significant change in cognition function detected in Nckx-/-mice. This study demonstrates that NCKX3 is involved in behavior and neuronal function.

Structure-function relationships of the NCKX2 Na+/Ca2+-K

K+-dependent Na+/Ca2+ exchangers (NCKX) have been shown to play important roles in physiological processes as diverse as phototransduction in rod photoreceptors, motor learning and memory in mice, and skin pigmentation in humans. Most structure-function studies on NCKX proteins have been carried out on the NCKX2 isoform, but sequence Structure-function relationships of the NCKX2 Na+/Ca2+-KK+-dependent Na+/Ca2+ exchangers (NCKX) have been shown to play important roles in physiological processes as diverse as phototransduction in rod photoreceptors, motor learning and memory in mice, and skin pigmentation in humans. Most structure-function studies on NCKX proteins have been carried out on the NCKX2 isoform, but sequence

Mitochondrial NCKX5 regulates melanosomal biogenesis and

We found that NCKX5 is localized to mitochondria, not to melanosomes. Pharmacological inhibition of mitochondrial function or NCKX exchanger activity reduced pigment production. Loss of NCKX5 attenuated Ca 2+ enrichment in melanosomes, which compromised PMEL fibril formation, melanosome maturation and pigment production. Mitochondrial NCKX5 regulates melanosomal biogenesis and We found that NCKX5 is localized to mitochondria, not to melanosomes. Pharmacological inhibition of mitochondrial function or NCKX exchanger activity reduced pigment production. Loss of NCKX5 attenuated Ca 2+ enrichment in melanosomes, which compromised PMEL fibril formation, melanosome maturation and pigment production.

Na+/Ca2+-K+ Exchangers (NCKX):Functional Properties and Physiological

The most numerous Ca 2+ extrusion protein family, in terms of distinct genes, is the SLC24 gene family of Na + /Ca 2+-K + exchangers (NCKX). Five distinct gene products have been identified, mostly from specific animal excitable tissues such as neurons and smooth muscle, but also in places like skin pigment epithelium, signifying that NCKX proteins may play Na+/Ca2+-K+ Exchangers (NCKX):Functional Properties and PhysiologicalThe most numerous Ca 2+ extrusion protein family, in terms of distinct genes, is the SLC24 gene family of Na + /Ca 2+-K + exchangers (NCKX). Five distinct gene products have been identified, mostly from specific animal excitable tissues such as neurons and smooth muscle, but also in places like skin pigment epithelium, signifying that NCKX proteins may play

Functional and Structural Properties of the NCKX2 Na

To clearly demonstrate functional differences between NCX and NCKX, we have undertaken measurements of K + dependence and Na + and Ca 2+ affinity under defined conditions of heterologous expression in HEK293 cells; for NCKX2, we used the human clone (Prinsen et al. 2000), while for NCX1 we used the canine clone (Nicoll et al. Functional and Structural Properties of the NCKX2 NaTo clearly demonstrate functional differences between NCX and NCKX, we have undertaken measurements of K + dependence and Na + and Ca 2+ affinity under defined conditions of heterologous expression in HEK293 cells; for NCKX2, we used the human clone (Prinsen et al. 2000), while for NCX1 we used the canine clone (Nicoll et al.

The SLC24 Na+/Ca2+-K+ exchanger family: vision and beyond

Na(+)/Ca(2+)-K(+) exchange (NCKX) was first discovered in the outer segments of vertebrate rod photoreceptors (ROS), where it is the only mechanism for extruding the Ca(2+) that enters ROS via the light-sensitive and cGMP-gated channels. ROS NCKX1 is the only NCKX gene family member studied extensiv The SLC24 Na+/Ca2+-K+ exchanger family: vision and beyondNa(+)/Ca(2+)-K(+) exchange (NCKX) was first discovered in the outer segments of vertebrate rod photoreceptors (ROS), where it is the only mechanism for extruding the Ca(2+) that enters ROS via the light-sensitive and cGMP-gated channels. ROS NCKX1 is the only NCKX gene family member studied extensiv

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone

Despite the critical role of Ca 2+ in supporting the function and survival of cones, the mechanism for its extrusion from cone outer segments is not well understood. Here, we show that the Na + /Ca 2+, K + exchanger NCKX4 is expressed in zebrafish, mouse, and primate cones. Functional analysis of NCKX4-deficient mouse cones The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone Despite the critical role of Ca 2+ in supporting the function and survival of cones, the mechanism for its extrusion from cone outer segments is not well understood. Here, we show that the Na + /Ca 2+, K + exchanger NCKX4 is expressed in zebrafish, mouse, and primate cones. Functional analysis of NCKX4-deficient mouse cones

manufacturing plants in Southeast Asia

Manufacturing Beyond China ForbesManufacturing Hubs Across Southeast Asia ASEAN Briefing. Aug 25 32 Manufacturing growth in Malaysia Southeast Asia’s third largest economy is buoyant with the production of passenger cars semiconductors Jul 22 32 This article is an excerpt from the July edition of Asia Briefing Magazine titled “Manufacturing manufacturing plants in Southeast AsiaManufacturing Beyond China ForbesManufacturing Hubs Across Southeast Asia ASEAN Briefing. Aug 25 32 Manufacturing growth in Malaysia Southeast Asia’s third largest economy is buoyant with the production of passenger cars semiconductors Jul 22 32 This article is an excerpt from the July edition of Asia Briefing Magazine titled “Manufacturing

A functional approach to understanding the role of NCKX5 in

SLC24A5 encodes NCKX5, a member of the NCKX family of potassium dependent sodium calcium exchangers [9, 10]. There are 4 other NCKX transmembrane proteins (1–4), which extrude calcium across the plasma membrane using the sodium potassium gradient. NCKX proteins are found in a variety of tissues, but their roles have A functional approach to understanding the role of NCKX5 inSLC24A5 encodes NCKX5, a member of the NCKX family of potassium dependent sodium calcium exchangers [9, 10]. There are 4 other NCKX transmembrane proteins (1–4), which extrude calcium across the plasma membrane using the sodium potassium gradient. NCKX proteins are found in a variety of tissues, but their roles have

鄂式破碎机-鄂式粉碎机生产厂家-河南红星矿山机器

鄂式破碎机价格. 红星工程师认真检查每一台机器，对残次品0容忍. 鄂式破碎机出现时间较早，所以各厂家对其生产技术都已经较为成熟，可以有效的控制生产成本。. 专业生产鄂式破碎机40年，生产的鄂式破碎机质量可靠、性能优，价格实惠，欢迎新老鄂式破碎机-鄂式粉碎机生产厂家-河南红星矿山机器鄂式破碎机价格. 红星工程师认真检查每一台机器，对残次品0容忍. 鄂式破碎机出现时间较早，所以各厂家对其生产技术都已经较为成熟，可以有效的控制生产成本。. 专业生产鄂式破碎机40年，生产的鄂式破碎机质量可靠、性能优，价格实惠，欢迎新老

智库网-资讯详情页

在航天科工江西科创中心，刘永才院士调研了南昌市院士工作站建设及中心科技创新服务运营发展情况。. 2016年底，依托与刘永才院士的合作项目，江西科创中心成功获准建立起南昌市院士专家工作站。. 在这期间，刘永才院士与中心签署了智能电子交互式教智库网-资讯详情页在航天科工江西科创中心，刘永才院士调研了南昌市院士工作站建设及中心科技创新服务运营发展情况。. 2016年底，依托与刘永才院士的合作项目，江西科创中心成功获准建立起南昌市院士专家工作站。. 在这期间，刘永才院士与中心签署了智能电子交互式教

颚式破碎机5个重要零部件的安装要点分析

4、颚式破碎机动颚的安装要点. 首先在地面上将动颚、动颚轴、肋板垫、活动齿板等零件组装完成后，使用吊车将组装好的部件一起放进破碎机机架里。. 对于滑动轴承，将滑动轴承研配好再放进机架轴承内，在允许范围内，可在轴承表面涂上润滑油，将动颚放颚式破碎机5个重要零部件的安装要点分析 4、颚式破碎机动颚的安装要点. 首先在地面上将动颚、动颚轴、肋板垫、活动齿板等零件组装完成后，使用吊车将组装好的部件一起放进破碎机机架里。. 对于滑动轴承，将滑动轴承研配好再放进机架轴承内，在允许范围内，可在轴承表面涂上润滑油，将动颚放

美卓C系列颚式破碎机详解.pdf-全文可读原创力文档

地面安装的正确选择诺德伯格C系列颚式破碎机是采石、卓越的破碎机更新换代产品成套破碎加工系统的全面专门技术矿山、采砾坑、甚至是循环回收利用等由于诺德伯格C系列颚式破碎机所占美卓设计并供应成套的矿岩破碎筛分地面固定破碎设备的理想美卓C系列颚式破碎机详解.pdf-全文可读原创力文档地面安装的正确选择诺德伯格C系列颚式破碎机是采石、卓越的破碎机更新换代产品成套破碎加工系统的全面专门技术矿山、采砾坑、甚至是循环回收利用等由于诺德伯格C系列颚式破碎机所占美卓设计并供应成套的矿岩破碎筛分地面固定破碎设备的理想

Na+/Ca2+ exchangers: three mammalian gene families control

10.1042/BJ20070619. Mammalian Na+/Ca2+ exchangers are members of three branches of a much larger family of transport proteins [the CaCA (Ca2+/cation antiporter) superfamily] whose main role is to provide control of Ca2+ flux across the plasma membranes or intracellular compartments. Since cytosolic levels of Ca2+ are much lower Na+/Ca2+ exchangers: three mammalian gene families control 10.1042/BJ20070619. Mammalian Na+/Ca2+ exchangers are members of three branches of a much larger family of transport proteins [the CaCA (Ca2+/cation antiporter) superfamily] whose main role is to provide control of Ca2+ flux across the plasma membranes or intracellular compartments. Since cytosolic levels of Ca2+ are much lower

Scanning mutagenesis of the alpha repeats and of the PubMed

Twenty-five residues were identified for which mutagenesis reduced NCKX function to <20% of wild-type cone NCKX2 activity, while protein expression and plasma membrane targeting were not affected. Three classes of residues were found to be most sensitive toward mutagenesis: acidic (glutamate/aspartate) residues, polar Scanning mutagenesis of the alpha repeats and of the PubMedTwenty-five residues were identified for which mutagenesis reduced NCKX function to <20% of wild-type cone NCKX2 activity, while protein expression and plasma membrane targeting were not affected. Three classes of residues were found to be most sensitive toward mutagenesis: acidic (glutamate/aspartate) residues, polar

NCX and NCKX operation in ischemic neurons PubMed

NCX and NCKX operation in ischemic neurons Ann N Y Acad Sci. 2007 Mar;1099:383-95. doi: 10.1196/annals.1387.035. Author Lech Kiedrowski 1 Affiliation 1 Department of Psychiatry, The Psychiatric Institute, 1601 W. Taylor St., Room 334W, Chicago, IL 60612, USA. [email protected]; PMID: 17446479 DOI NCX and NCKX operation in ischemic neurons PubMedNCX and NCKX operation in ischemic neurons Ann N Y Acad Sci. 2007 Mar;1099:383-95. doi: 10.1196/annals.1387.035. Author Lech Kiedrowski 1 Affiliation 1 Department of Psychiatry, The Psychiatric Institute, 1601 W. Taylor St., Room 334W, Chicago, IL 60612, USA. [email protected]; PMID: 17446479 DOI

农村科学实验

农村科学实验. 《农村科学实验》杂志，投稿方式以在线投稿（nckx.cbpt.cnki.net）和邮箱投稿（nckxsy@qq）为准，来稿要求如下：. 1. 题目. 中文题名一般不超过20个汉字。. 题名应简明、具体、确切，概括文章的要旨，符合编制题录、索引和检索的有关原则，并有农村科学实验农村科学实验. 《农村科学实验》杂志，投稿方式以在线投稿（nckx.cbpt.cnki.net）和邮箱投稿（nckxsy@qq）为准，来稿要求如下：. 1. 题目. 中文题名一般不超过20个汉字。. 题名应简明、具体、确切，概括文章的要旨，符合编制题录、索引和检索的有关原则，并有

Structure-function relationships of K +-dependent Na +/Ca 2

K +-dependent Na + /Ca 2+ exchanger proteins (NCKX1-5) of the SLC24 gene family play important roles in a wide range of biological processes including but not limited to rod and cone photoreceptor vision, olfaction, enamel formation and skin pigmentation. NCKX proteins are also widely expressed throughout the brain and NCKX2 and NCKX4 Structure-function relationships of K +-dependent Na +/Ca 2K +-dependent Na + /Ca 2+ exchanger proteins (NCKX1-5) of the SLC24 gene family play important roles in a wide range of biological processes including but not limited to rod and cone photoreceptor vision, olfaction, enamel formation and skin pigmentation. NCKX proteins are also widely expressed throughout the brain and NCKX2 and NCKX4

The Archaeal Na +/Ca 2+ Exchanger (NCX_Mj) as a Model of Ion PubMed

The superfamily of Calcium/Cation (Ca 2+ /CA) antiporters extrude Ca 2+ from the cytosol or subcellular compartments in exchange with Na +, K +, H +, Li +, or Mg 2+ and thereby provide a key mechanism for Ca 2+ signaling and ion homeostasis in biological systems ranging from bacteria to humans. The structure-dynamic determinants of ion The Archaeal Na +/Ca 2+ Exchanger (NCX_Mj) as a Model of Ion PubMedThe superfamily of Calcium/Cation (Ca 2+ /CA) antiporters extrude Ca 2+ from the cytosol or subcellular compartments in exchange with Na +, K +, H +, Li +, or Mg 2+ and thereby provide a key mechanism for Ca 2+ signaling and ion homeostasis in biological systems ranging from bacteria to humans. The structure-dynamic determinants of ion

Functional and structural properties of the NCKX2 Na(+)-Ca (2+)/K

But, unlike NCX, much less is known about the physiological roles of NCKX, while emergent evidence indicates that NCKX has highly specialized functions in cells and tissues where it is expressed. As their name implies, there are functional similarities in the properties of the two Ca(2+) exchanger families, but there are specific differences as well. Functional and structural properties of the NCKX2 Na(+)-Ca (2+)/KBut, unlike NCX, much less is known about the physiological roles of NCKX, while emergent evidence indicates that NCKX has highly specialized functions in cells and tissues where it is expressed. As their name implies, there are functional similarities in the properties of the two Ca(2+) exchanger families, but there are specific differences as well.

NCKX4 CRISPR基因敲除和激活产品 (h) SCBIO Santa Cruz

NCKX4 CRISPR 质粒 (h) /. Click on image or enlarge button to enlarge. Each CRISPR/Cas9 Knockout (KO) Plasmid product consists of a pool of 3 plasmids designed to ensure identification and cleavage of a specific gene for maximum knockout efficiency. Each plasmid encodes a unique 20 nt sequence derived from the GeCKO (v2) library. NCKX4 CRISPR基因敲除和激活产品 (h) SCBIO Santa CruzNCKX4 CRISPR 质粒 (h) /. Click on image or enlarge button to enlarge. Each CRISPR/Cas9 Knockout (KO) Plasmid product consists of a pool of 3 plasmids designed to ensure identification and cleavage of a specific gene for maximum knockout efficiency. Each plasmid encodes a unique 20 nt sequence derived from the GeCKO (v2) library.

SLC24A2 solute carrier family 24 member 2 [ (human)]

This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light SLC24A2 solute carrier family 24 member 2 [ (human)]This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light

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